MyBioSource.com's ITGB2 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Western Blot. The ITGB2 Antibody was generated using ITGB2 as the antigen and it reacts with Human.
Description
The product of this gene belongs to the integrin beta
chain family of proteins. Integrins are integral cell-surface
proteins composed of an alpha chain and a beta chain. This gene
encodes the integrin beta chain beta 2. A given chain may combine
with multiple partners resulting in different integrins. For
example, beta 2 combines with the alpha L chain to form the
integrin LFA-1, and combines with the alpha M chain to form the
integrin Mac-1. Integrins are known to participate in cell adhesion
as well as cell-surface mediated signalling. Defects in this gene
are the cause of leukocyte adhesion deficiency type I (LAD1). Two
transcript variants encoding the same protein have been identified
for this gene